The Principle of Fair and Equitable Treatment

Free Essays on My Trip To Scotland

My Trip to Scotland My trip to St. Andrews, Scotland, was an experience unlike any other experience in my life. Going, I didn’t know quite what to expect. I did expect Scottish life to be somewhat different. However, I was surprised at just how different it was. I had many memorable experiences during my trip to Scotland. I loved just listening to the Scottish people talk; listening to their occasionally incomprehensible accents and their never-ending supply of wonderful tales was mesmerizing. I enjoyed the relaxed lifestyle and kind, fun-loving nature of the Scottish people. I adored the openness and unity in Scotland, and especially how I had to wait for pedestrians to get out of my way at the 1st and 18th holes of The Old Course before taking my next shot. I trembled on the edge of my seat while driving through little Scottish country towns, marked by their beauty and their simplicity, on a tiny road where certain accident seemed to await us at every turn. I was shocked that we, and our rental car, came back in one piece. However, of all of my memorable moments in Scotland, one stands out in my memory as an unforgettable experience, an experience that truly expanded my horizons: playing golf at The Old Course at St. Andrews. The Old Course at St. Andrews is the oldest golf course still being played today. It has played host to many important golf tournaments and the best golfers in history. Simply getting on the golf course to play required extreme cunning and scheming by my astute and determined father. After the lottery system, which determines who gets to play, turned out unsuccessful for our hopeful two-some, my father came up with a brilliant idea. He used his charm, his wit, and his â€Å"I want to take my son out for a good ol’ father and son golfing trip on the most historic golf course in the world† story to persuade the starter to squeeze us into a tee time. It was either that approach or the free Bo... Free Essays on My Trip To Scotland Free Essays on My Trip To Scotland My Trip to Scotland My trip to St. Andrews, Scotland, was an experience unlike any other experience in my life. Going, I didn’t know quite what to expect. I did expect Scottish life to be somewhat different. However, I was surprised at just how different it was. I had many memorable experiences during my trip to Scotland. I loved just listening to the Scottish people talk; listening to their occasionally incomprehensible accents and their never-ending supply of wonderful tales was mesmerizing. I enjoyed the relaxed lifestyle and kind, fun-loving nature of the Scottish people. I adored the openness and unity in Scotland, and especially how I had to wait for pedestrians to get out of my way at the 1st and 18th holes of The Old Course before taking my next shot. I trembled on the edge of my seat while driving through little Scottish country towns, marked by their beauty and their simplicity, on a tiny road where certain accident seemed to await us at every turn. I was shocked that we, and our rental car, came back in one piece. However, of all of my memorable moments in Scotland, one stands out in my memory as an unforgettable experience, an experience that truly expanded my horizons: playing golf at The Old Course at St. Andrews. The Old Course at St. Andrews is the oldest golf course still being played today. It has played host to many important golf tournaments and the best golfers in history. Simply getting on the golf course to play required extreme cunning and scheming by my astute and determined father. After the lottery system, which determines who gets to play, turned out unsuccessful for our hopeful two-some, my father came up with a brilliant idea. He used his charm, his wit, and his â€Å"I want to take my son out for a good ol’ father and son golfing trip on the most historic golf course in the world† story to persuade the starter to squeeze us into a tee time. It was either that approach or the free Bo...

AED (Automated External Defibrillator) and their need in the community Research Proposal

AED (Automated External Defibrillator) and their need in the community - Research Proposal Example Of these, 7.6 million were due to CHD. It has been estimated that by 2015, approximately 20 million people will die from cardiovascular disease (World Health Organization). 80,700,000 Americans suffer from CVD. 73,000,000 have HBP, 16,000,000 have CHD, 5,300,000 suffer from heart failure, and 650,000-1,300,000 have congenital cardiovascular defects. In the age group 20-39 less than 20 percent of the population suffer from CVD. 39 percent of the population in the age group 40-59 suffer from some form of CVD. More than 70 percent of the population in the age group 60-79 suffer from some form of CVD. More than 80 percent of the population over 80 years suffer from some form of CVD. CVD accounted for 869,724 of all 2,397,615 deaths in 2004. Approximately 250,000 deaths result from heart attacks annually. It has been estimated that the annual incidence of heart attack is 600,000 new attacks and 320,000 recurrent attacks. More than 148,000 were under 65. 2,400 Americans die of CVD each day. 310,000 deaths occur out-of-hospital or in hospital emergency departments. Statistics show that an American will suffer a coronary event every 26 seconds, and about every minute someone will die from one. 38 percent of the people experiencing a coronary attack in a given year will die. 82 percent of people dying of CHD are 65 years or older. CHD caused one in five deaths among Americans in 2004. More people died from CVD than from Cancer in 2004. CVD ranked highest among disease categories in hospital discharges in 2005. Life expectancy would increase by seven years if all forms of CVD were eliminated ("Heart Disease and Stroke Statistics" 1-40). According to the World Health Organization, deaths by heart attacks are preventable. CPR and defibrillation within the first few minutes after collapse, followed by advanced care can result in high survival rates. 20,000 lives could be saved annually by the use of Automated External

Waste Disposal and Green Intelligence Dissertation

Waste Disposal and Green Intelligence - Dissertation Example The government should play a crucial role in ensuring that citizens are made aware of the best and most convenient ways of managing waste. Waste recycling is one of the interventions that most governments especially in first-world countries have taken to deal with waste management. For example, the U.S government has carried out campaigns to sensitize its citizens on the importance of recycling materials such as plastics, paper, and glass. In as far as land filling is concerned; the government advices that the dug up surfaces should have bottom liners to collect any water that may contain hazardous chemicals. This way no toxic water flows into the ecosystem. Concerning disposal of wastes into water bodies, the U.S government directs that industrial wastes be deactivated before being released into water bodies.The main goal of green intelligence is to provide the general public with information concerning the dangers they are exposed to as a result of poor waste management. This invol ves using market-oriented approaches to ensure environmental sustainability and conservation of natural resources .Green intelligence strategizes to achieve its goal by urging the private sector and the government to avail necessary information to the public. This is because the government and private sector seem to be colluding to hide trivial information from the public on hazardous substances and poor waste management. According to Wargo, chemical manufacturers are very crucial in ensuring a safe environment and a healthy general public.

Inflammatory Mediators Of Asthma Health Essay

Inflammatory Mediators Of Asthma Health Essay Once IgE binds to mast cells (or activated eosinophils), an amplification system operates since the cells not only release the spasmogens and other mediators specified but also can stimulate ÃŽ ² cells to produce more IgE. Furthermore, the production of IL-5, IL-4 IL-13 and IL-9 amplifies the Th2-mediated events. It is believed that asthma symptoms are manifested because of Th2 mediated immune response. Pulmonary allergic inflammation in mice lead to decrease in pulmonary IL-5 concentration, specific IgE, IgG1, and eosinophil and T cell recruitment in wild type mice in the absence of T cells. T cells are important in IL-4 dependent IgG1, IgE and Th2 cell mediated lung inflammation, further more there is evidence that CD4+T cells have a role in asthma process. For example, in murine model external protein induced T cells increases IL-5 production and produces airway eosinophilia. (Larche et al. 2003) Asthma is a complex chronic inflammatory airway disorder that involves the activation of the inflammatory and structural cells. These released inflammatory mediators cause typical pathophysiological changes of asthma (Peter et al., 2003). There are several lines of evidence that may implicate a mediator in asthma. Firstly, it may mimic features of clinical asthma. Secondly, the mediator may be produced in asthmatic patients. Thus, mediators or their metabolites may be detected in plasma (e.g. histamine), urine (e.g. LTE4), or more likely, the airways in biopsies, bronchoalveolar lavage fluid, induced sputum or exhaled air. 1.8.3.1. Histamine Histamine was the first mediator implicated in the pathophysiological changes of asthma (Barnes et al., 1998). Histamine is one of the important mediator of allergy, inflammation and bronchoconstriction. Histamine is synthesized and released by mast cells in the airway wall and by circulating and infiltrating basophils. Antigen-induced histamine secretion is initiated by the bridging of the adjacent IgE receptors on the mast cell surface. Histamine receptors are among the thousands of members of the 7-transmembrane-spanning family of receptors that couple ligand binding to intracellular reactions through interactions with another large family of guanosine triphosphate (GTP)-binding heterotrimeric proteins. H1-receptors mediate a host of intracellular events most readily characterized by changes in free cytosolic calcium levels. Histamine show different response in mammalian tissue depends upon presence of receptor on that tissue Kulkarni, (1976). 1.8.3.2. Adenosine Adenosine can act as an autocoid cause bronchoconstriction in asthmatics and increase immunologically induced mediator release from mast cells of human lung (Cushley et al., 1984; Peachell et al., 1988). Mast cells also release adenosine in response to IgE cross-linking and other stimuli for mast cell activation. 1.8.3.3. Lipid-Derived Mediators Leukotrienes Leukotrienes are potent lipid mediators produced by arachidonic acid metabolism in cell or nuclear membrane. Several types of airway inflammatory cells, like eosinophils, macrophages, mast cells, neutrophils, and epithelial cells, can synthesize LTs in response to a variety of stimuli. Leukotrienes are important inflammatory mediators involved in the pathogenesis of asthma. All the Cys-LTs are potent constrictors of bronchial smooth muscle. On a molar basis, LTD4 is 1000 times more active than histamine and constrict bronchioles (Dahlen et al., 1980). Cys-LTs, acting on Cys-LT1 receptors produce bronchospasm, airway hyper-responsiveness, proliferation of airway smooth muscle, excess production of mucus and mucosal edema and eosinophilia in the airways, and other features in asthma (Sundeep et al., 2001; Peter, 1998). Platelet Activating Factor (PAF) PAF is ether-linked phospholipid. The synthesis of PAF occurs in inflammatory cells, including platelet, neutrophils, basophils, macrophages and eosinophils. PAF induces airway smooth muscle contraction by releasing other mediators. PAF-induced bronchoconstriction is not inhibited by H1 receptor antagonist Ketotifen. However, PAF-induced bronchoconstriction can be inhibited by LT antagonists, because of involvement of LTD4 in this response. PAF stimulate chemotaxis and adhesion of eosinophils and neutrophils in-vitro (Peter et al., 2003). Prostanoids Prostanoids include prostaglandins (PGs) and thromboxane (Tx), which are generated from arachidonic acid, usually by the action of COX. In general PGF2 and PGD2 contract and PGE relax tracheal muscle. Asthmatic individuals are particularly sensitive to PGF2ÃŽ ±, which may cause intense bronchospasm. Although both PGE1 and PGE2 can produce bronchodilatation when given to such patients by aerosol, bronchoconstriction sometime is observed. Tx analogue U 46619 is a potent constrictor in asthmatic patients, and this effect is mediated in part via acetylcholine release. Prostanoids stimulate airway mucus secretion in various animal species. It inhibits the release of mediators from mast cells, monocytes, neutrophils and eosinophil inflammatory cells (Peter et al., 2003). 1.8.3.4. Cytokines Cytokines are small protein mediators that play an integral role in the coordination and persistence of inflammation in asthma. Many inflammatory cells macrophages, mast cells, eosinophils and lymphocytes) are capable of synthesizing and releasing these proteins. Th2 lymphocytes produce a panel of cytokines, including IL-5, IL-4, IL-13 and IL-9 (Barnes et al., 1998). 1.8.3.4.1. Interleukin-4 IL-4 is critical for the synthesis of IgE by B-cells and for eosinophils recruitment. IL-4 is also involved in Th2 cell differentiation. IL-4 is a key factor in the development of allergic inflammation, and they may also play a major role in exacerbating asthmatic symptoms (Adcock and Caramori, 2003). Figure 11. Role of CD4+Th2cells and Various cytokines in asthma pathogenesis. 1.8.3.4.2. Interleukin-5 It play important role in allergic asthma. IL-5 promote the maturation of eosinophils from bone marrow processor, prolongs their survival by inhibition of apoptosis, activates mature eosinophil recruitment to tissue via synergistic effect with chemoattractants such as eotaxin and promote eosinophil adhesion of vascular endothelium.IL-5 can also promote basophils to release exaggerated amounts of histamine and leukotrienes, mediators that contribute to allergic bronchospasm and congestion in asthma (Fred et al., 2000). 1.8.3.4.3. Interleukin-9 Its major actions include maturation of eosinophils, airway inflammation, airway hyper-responsiveness and mucus over production (Adcock and Caramori, 2003). 1.8.3.4.4. Interleukin-13 IL-13 is critical for the synthesis of IgE by B-cells. Activates eosinophils, monocyte. IL-13 is a key factor in the development of allergic inflammation and they may also play a major role in exacerbating asthmatic symptoms (Barnes et al., 1998). 1.8.3.5. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) GM-CSF is one of the colony-stimulating factor that acts to regulate the growth, proliferation and maturation of hematopoietic cells.GM-CSF can enhance the release of superoxide anions, also induce eosinophil apoptosis and activation, induces release of LTs, endothelial cell migration (Barnes et al., 1998). 1.8.3.6. Reactive Oxygen Species in Asthma Reactive oxygen species (ROS) are generated by various enzymatic reactions and chemical processes or they can directly be inhaled. ROS are essential in many physiological reactions and are important for the killing of invading microorganisms. However, when airway cells and tissues are exposed to oxidative stress elicited by environmental pollutants, infections, inflammatory reactions or decreased levels of anti- oxidants, enhanced levels of ROS can have a variety of deleterious effects within the airways thereby inducing several pathophysiological conditions. It has been shown that ROS can damage DNA, lipids, proteins and carbohydrates leading to impaired cellular functions and enhanced inflammatory reactions. ROS are known to play a prominent role in the pathogenesis of various airway disorders such as adult respiratory distress syndrome (ARDS), cystic fibrosis, idiopathic fibrosis, chronic obstructive pulmonary diseases (COPD) and asthma (Gillissen and Nowak, 1998; Repine et al., 1997).

To Have Or Not To Have Caesarean Section Essay example -- essays paper

To Have Or Not To Have Caesarean Section Years ago caesarean section (c-section) was only done in cases of emergency such as when the mother’s life or the neonate’s life is in danger. However at the turn of the century, there seems to have a remarkable rise in c-section deliveries. It seems that women nowadays are willing to take the risk of surgery to avoid the stress and pain of labor rather than experience the normal trend of delivering a baby vaginally – the normal way. The majority of pregnant women believe that the best method of giving birth is the least painful but this is not necessarily the safest (Ghetti, Chan & Guise 2004). Amazingly some obstetricians have become advocates for this surgical procedure instead of advisors to what is really suitable for the individual. What it is that drives women to go for a mutilating procedure rather than a simple laceration of a normal birth? The answer is obvious. The modern women are scared of pain, of the long stretch of labor and the stress that comes along with it. But what the modern women should understand is that delivering babies by caesarean section is not the answer to a pain-free delivery (Smeltzer & Bare, 2002). Caesarean Section – Its Beginning Many people think that c-section is a modern method of delivering babies. The truth is, â€Å"†¦ caesarean section has been a part of human culture since the ancient times†¦Ã¢â‚¬ (The National Institute of Health Convention, 1998). In fact history tells about the birth of Julius Caesar by c-section, thus the term â€Å"caesarean† came into use. However, modern historians do not believe that Julius Caesar ‘s birth was by c-section since his mother had been mentioned in some part of history to be alive when Caesar was already a reigning ... ...Ghetti,C., Chan, BKS., & Guise, J. (2004). Physicians’ responses to patient requested-caesarean delivery. Retrieved March 2, 2005 form www.cinahl/chi-bin/refsvc Ignatavicious, D. & Workman, L. (2001). Medical-surgical nursing: Critical thinking collaborative care. (4thed.). Philadelphia, PA: Mosby, Inc. Lowdermilk, D. & Peryy, S. (2004). Maternity and women’s health care. (4th ed.). St. Louise, MO: Mosby, Inc. Porter, M. & Bhattachary, S. (2004). Preventing unnecessary caesarean section: Marginal benefit of a second opinion. The Lancet. 364, 1921. Rubin, R. (2004). Do you have a choice? USA Today, Sept.16, 2004, D-08. Smeltzer, S.C. & Bare, B. (2002). Medical-surgical nursing. (9thed.). Philadelphia, PA: Lippincott Williams & Wilkins. Stein, R. (2004). Findings on caesarean section rekindle debate. The Washington Post, Dec. 15, 2004, p. A-18.

Marc Antony’s Soliloquy: An Analysis

My transformation of the Shakespearean text employs many different grammatical features to create an effective, modern version of Marc Antony’s soliloquy. Features such as nominalisation, paragraphing and abstract noun groups are a few of the features used. My transformation is suitable for modern audiences, using both language and people that today’s society is familiar with. My transformed version of the soliloquy uses many grammatical techniques and features to make it as interesting and grammatically correct as possible, whilst making it a piece of writing that people today are used to reading and/or hearing. Nominalisation is an important grammatical feature, which allows you to increase the levels of linguistic complexity as the text becomes more abstract, through leaving out the action of the nominalised verb. Words like ability, possibly and determination are all examples of nominalisation, and give more meaning into a sentence without needing to make the sentence longer than necessary. Overall, this gives the text as a whole more depth and meaning. The paragraphing used sets out the different ideas being introduced into the text, organising them into different paragraphs where all the ideas flow together. Sentence structures tie together the text, ensuring that ideas flow and it is more interesting for the reader. Using different sentence types, like compound and complex, mixes up the text a bit and keeps readers engaged as they continue to read the text. Obviously, people are more likely to continue to read something if they are interested in it, and I wanted my speech to engage readers and listeners. Clause combinations help to set out and organise ideas nicely, using different types of sentences to again create interest. I have used abstract noun groups to involve the listeners in the text, letting them connect with the speech through them using their pre-conceived ideas of what the words mean. Abstract nouns, being things that you can’t actually see or touch, means that listeners have to substitute in what their meaning of the word is, therefore making them think about the text more. I wanted my speech to make people think, and the use of abstract nouns helps to achieve that. Abstract noun groups such as ‘kind-hearted and generous, strong willed and fair’ are examples of this. When I first started the modern version, I had in my mind a clear image of what I wanted it to be like. With using the different techniques and features, I believe I’ve reached my idea of what I wanted. One of the hardest things that I was faced with when I started to re-write the soliloquy was who to write about, and who’s perspective to write from. After a lot of thought, I finally decided on Margaret Thatcher and Tony Blair. I thought that it would be a good fit, for numerous reasons. Both Caesar and Thatcher were controversial people. Both had their lovers and their haters, and there was never really an in between. They were both major political figures of their time, and had large effects on their society during their rein. Not only did I feel they shared many similarities, but I’ve always been interested in Thatcher. It seems that both Caesar and Thatcher were very strong-willed, and knew exactly what they wanted. In Antony’s speech, he was mainly paying tribute to Caesar, and I knew that a figure such as Tony Blair would do the same for Thatcher. Having both speeches set at a funeral made sure that similarities were kept, same as the references to ‘after a person dies, the bad is remembered and the good forgotten’. Whilst I tried as much as I could to modernise the text, I tried to keep it quite formal. This is obviously because the speech is being performed by an ex-Prime Minister at another ex-Prime Minister’s funeral, which is quite the formal occasion. In the Shakespearean version, Antony talks about how Brutus says that Caesar is an honourable man, but he believes differently. In my version, Blair speaks about how many people often loathed Thatcher. In this, I have both similarities and differences. The language I have used is more modern, employing slang and generally newer ways of speaking. Overall, I’m very happy with my transformation of the Shakespearean text. The different grammatical features used has made the soliloquy very effective. My version is suitable for modern readers, and follows the basic storyline the original soliloquy uses.